Practice Test 11 - USMLE Step 1

20 questions. Answer them in any order, then submit to see your score and every explanation.

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1. The physician's statement, "I think it could really help you," has the potential to create which of the following ethical problems?
2. Which of the following characteristics would most strongly support the implementation of a screening program?
3. A 41-year-old man presents with acute Achilles tendon rupture 2 days after beginning ciprofloxacin for pyelonephritis. Which feature of fluoroquinolone pharmacodynamics most closely relates to this adverse event?
4. Dobutamine exerts these effects primarily through which of the following mechanisms?
5. Right gaze: left eye fails to adduct, right eye nystagmus; convergence intact. Lesion site?
6. This mutation most likely impairs which of the following properties of the enzyme?
7. The refractory hypocalcemia in this patient is best explained by the low magnesium level's effect on which of the following?
8. Which of the following represents the most likely mechanism of action of the prescribed drug?
9. Which of the following molecular modifications is the primary mechanism responsible for establishing and maintaining the parent-specific imprinting of these genes?
10. Which of the following findings is most expected on this patient's muscle biopsy, and what does it represent?
11. The final TCA cycle intermediate produced from propionyl-CoA metabolism is which of the following?
12. Based on these findings, which of the following best describes the net handling of substance Y by the renal tubules?
13. Based on this information, which of the following is the most accurate conclusion?
14. Which of the following is the initial event in the pathogenesis of secondary hyperparathyroidism in this patient with chronic kidney disease?
15. Which of the following is the most likely underlying genetic mechanism responsible for this infant's condition?
16. The renal pathology in this patient is best described by which of the following mechanisms?
17. The pathogenesis of this patient's cardiac findings is best explained by which of the following mechanisms of autoimmune induction?
18. This addition of N-nucleotides at gene segment junctions is catalyzed by which of the following enzymes?
19. Which of the following proteins prevents endogenous peptides in the endoplasmic reticulum from binding to the peptide-binding groove of newly synthesized MHC class II molecules?
20. This patient's condition is most likely inherited in which of the following patterns?

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