Pharmacology Quiz
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CARDIOVASCULAR & RENAL PHARMACOLOGY
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A patient with newly diagnosed deep vein thrombosis (DVT) is initiated on therapy with both a continuous heparin infusion and oral warfarin. On day 3 of therapy, the patient's activated partial thromboplastin time (aPTT) is therapeutic, and the INR is 2.3. A colleague suggests discontinuing the heparin infusion.
Why would discontinuing heparin at this point be potentially unsafe, despite the therapeutic INR?
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