Pharmacology Quiz
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TOXICOLOGY & SPECIAL POPULATIONS
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A 68-year-old male with septic shock is in the ICU. His baseline serum creatinine (SCr) was 1.0 mg/dL. Over the past 24 hours, his SCr has rapidly increased to 2.8 mg/dL and his urine output has decreased significantly. He requires initiation of vancomycin, which is dosed based on renal function. Which of the following is the most appropriate consideration for determining the initial vancomycin regimen?
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