Insulin Regimens And Hypoglycemia Management - NCLEX Rn
- Which insulin type provides basal coverage with minimal or no peak (examples: glargine, detemir, degludec)?
- Long-acting insulin (basal, minimal peak). Maintains steady basal insulin levels without significant peaks to mimic natural background insulin secretion.
- What is the standard injection route for routine outpatient insulin administration?
- Subcutaneous injection. Subcutaneous route allows for controlled absorption rates suitable for various insulin durations in daily management.
- Which insulin is appropriate for IV infusion in emergencies such as DKA or severe hyperkalemia?
- Regular insulin (IV). Only regular insulin is stable for IV use, enabling rapid correction in acute hyperglycemia or hyperkalemia.
- Which option is appropriate when a patient is NPO: hold prandial insulin or hold basal insulin?
- Hold prandial insulin; usually continue basal per order. Prandial covers meals, so hold when NPO; basal maintains fasting control and prevents ketosis.
- Identify the blood glucose threshold commonly used to define hypoglycemia in adults.
- Blood glucose < mg/dL. Threshold indicates impaired counterregulation, requiring intervention to prevent symptoms and complications.
- After giving g of carbohydrate for hypoglycemia, when should blood glucose be rechecked?
- Recheck in minutes. Allows time for carbohydrate absorption and glucose rise, guiding need for further treatment.
- Which insulin type is used for mealtime coverage with onset about 30–60 minutes (example: regular insulin)?
- Short-acting insulin (regular). Offers mealtime coverage with a delayed onset, allowing administration 30 minutes before eating to match glucose rise.
- Identify the best immediate action for an unconscious hypoglycemic patient without IV access.
- Administer glucagon IM or SQ. Glucagon mobilizes stored glucose, essential when unable to use oral or IV methods.
- Identify the correct action if a patient is hypoglycemic and scheduled for rapid-acting insulin now.
- Treat hypoglycemia first; hold insulin until glucose recovers. Prioritizes resolving low glucose to avoid worsening with additional insulin administration.
- If blood glucose remains < mg/dL after minutes, what is the next action?
- Repeat g carbohydrate and recheck in min. Follows the rule of 15 to incrementally correct persistent low glucose without overcorrection.
- What is the immediate treatment for mild hypoglycemia in a conscious patient who can swallow?
- Give g fast-acting carbohydrate PO. Rapidly raises blood glucose via simple sugars that are quickly absorbed without digestion.
- Which option best prevents hypoglycemia during increased physical activity for an insulin-treated patient?
- Increase carbohydrates or reduce insulin per plan. Balances increased glucose utilization during activity to maintain euglycemia.
- What medication is used for severe hypoglycemia when there is no IV access available?
- Glucagon IM or SQ. Stimulates hepatic glycogenolysis to release glucose when oral or IV routes are unavailable.
- Identify the correct injection site teaching to reduce lipodystrophy with repeated insulin injections.
- Rotate sites within the same anatomic area. Rotation minimizes tissue damage and ensures consistent absorption by avoiding overused sites.
- What is the primary purpose of basal insulin in a basal–bolus regimen?
- Controls fasting and between-meal glucose. Provides continuous low-level insulin to suppress hepatic glucose production during fasting periods.
- After glucagon is given and the patient awakens, what should be administered next to prevent recurrence?
- Oral carbohydrate plus protein/complex carb snack. Provides sustained glucose to counteract glucagon's temporary effect and prevent rebound hypoglycemia.
- What is the preferred treatment for severe hypoglycemia when the patient cannot take oral glucose but has IV access?
- IV dextrose (e.g., DW per protocol). Delivers concentrated glucose directly into bloodstream for fast reversal of severe symptoms.
- Which insulin type is used for basal coverage with a peak (example: NPH insulin)?
- Intermediate-acting insulin (NPH). Delivers sustained basal insulin with a peak action to cover glucose needs over 12-18 hours.
- When drawing up NPH and regular insulin in one syringe, which is drawn up first?
- Regular insulin first (clear before cloudy). Drawing clear regular insulin first prevents contamination of the vial with cloudy NPH, ensuring stability.
- Which adrenergic symptom is a classic early sign of hypoglycemia in a conscious patient?
- Diaphoresis and tremor. Adrenergic response from catecholamine release alerts to falling glucose, prompting early intervention.
- Which insulin type has the fastest onset and is given with meals (examples: lispro, aspart, glulisine)?
- Rapid-acting insulin. Provides quick coverage for carbohydrate intake due to onset within 15 minutes, preventing postprandial hyperglycemia.
- What is the key nursing action to reduce hypoglycemia risk when giving rapid-acting insulin?
- Ensure meal is available and patient will eat. Timing insulin with food intake prevents unmatched insulin action leading to low blood glucose.
- What is the primary purpose of bolus (prandial) insulin in a basal–bolus regimen?
- Controls postprandial glucose rises. Rapidly counters glucose elevation from meals by mimicking post-meal insulin release.
- Which neuroglycopenic symptom indicates severe hypoglycemia risk (priority finding)?
- Altered mental status or confusion. Brain glucose deprivation causes cognitive impairment, signaling urgent need for glucose restoration.
- Which insulin should not be mixed with other insulins in the same syringe (common NCLEX rule)?
- Insulin glargine (do not mix). Glargine's acidic pH causes precipitation if mixed, leading to altered pharmacokinetics and ineffective action.