NAPLEX Quiz
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A 38-year-old male (90 kg) is admitted for suspected meningitis and started empirically on ceftriaxone 2 g IV every 12 hours plus vancomycin IV plus ampicillin 2 g IV every 4 hours. Current meds: none. Labs: SCr 0.9 mg/dL; AST/ALT 20/19 units/L; WBC 18.0 x103x10^3/mcL. CSF culture grows Neisseria meningitidis susceptible to penicillin; blood cultures pending. Allergy: none. Which intervention is most appropriate for this patient's antimicrobial therapy?
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