Pharmacokinetic Parameters
NAPLEX · Flashcards · Application
NAPLEX · FLASHCARDS
Card 1
of 4
0 got it
0 to review
Current
Got it
Still learning
Not seen
QUESTION
Calculate
V
V
V
if
D
o
s
e
=
400
mg
Dose = 400\ \text{mg}
D
ose
=
400
mg
IV bolus and
C
0
=
10
mg
/
L
C_0 = 10\ \text{mg}/\text{L}
C
0
=
10
mg
/
L
.
QUESTION
Calculate
t
1
2
t_{\frac{1}{2}}
t
2
1
if
k
=
0.2
h
−
1
k = 0.2\ \text{h}^{-1}
k
=
0.2
h
−
1
for first-order elimination.
QUESTION
Calculate
C
L
CL
C
L
if
D
o
s
e
=
500
mg
Dose = 500\ \text{mg}
D
ose
=
500
mg
IV and
A
U
C
=
50
mg
⋅
h
/
L
AUC = 50\ \text{mg}\cdot\text{h}/\text{L}
A
U
C
=
50
mg
⋅
h
/
L
.
Tap to flip before you grade
ANSWER
C
L
=
500
50
=
10
L
/
h
CL = \frac{500}{50} = 10\ \text{L}/\text{h}
C
L
=
50
500
=
10
L
/
h
. Clearance is dose divided by AUC, reflecting elimination efficiency for IV administration.
Swipe → got it · swipe ← still learning
Got it
Still learning
Flip Card
Previous card
Next card