How Humans Change Traits - Middle School Life Science

  1. What is gene editing (for example, CRISPR) designed to do to DNA?
    Precisely add, remove, or change specific DNA sequences. Allows targeted genetic changes at specific locations.
  2. Identify the main goal of selective breeding in crops or livestock.
    To produce offspring with more desirable traits. Improves crops and livestock for human benefit.
  3. What is heredity?
    Passing genetic information and traits from parents to offspring. How traits are inherited through generations.
  4. What is a major risk of inbreeding for a population?
    Reduced genetic diversity and increased chance of harmful traits. Less variation makes populations vulnerable to disease.
  5. What is a common risk of inbreeding?
    Higher chance of harmful recessive traits and genetic disorders. Related parents share more harmful alleles that can pair up.
  6. What is a trait in genetics?
    A characteristic influenced by genes and often by the environment. Observable features determined by genetics.
  7. What is a major goal of selective breeding in crops?
    Increase yield, quality, or resistance to pests and disease. Farmers select for traits that improve crop productivity and survival.
  8. What is a transgenic organism?
    An organism with a gene inserted from a different species. Contains DNA from another species through genetic engineering.
  9. Which option is an example of selective breeding rather than genetic engineering: Bt corn or dog breeds?
    Dog breeds. Dogs were bred over centuries; Bt corn has inserted bacterial genes.
  10. What is heterosis (hybrid vigor)?
    Hybrids show stronger growth or health than either parent line. Mixed genetics often produces healthier offspring than pure lines.
  11. What does selective breeding change in a population over many generations?
    It increases the frequency of alleles for chosen traits. Desired alleles become more common through selection.
  12. What is selective breeding (artificial selection)?
    Human-directed breeding to increase desired inherited traits. Humans control mating to enhance specific traits over generations.
  13. Which term describes breeding two different breeds to combine useful traits?
    Crossbreeding. Mixing breeds combines complementary traits from each parent.
  14. What is one major risk of inbreeding for a population?
    Increased chance of harmful recessive traits appearing. Related parents share more harmful recessive alleles.
  15. Identify the most likely outcome of repeatedly breeding only the fastest racehorses.
    Average speed increases as speed-related alleles become more common. Selection for speed genes increases their proportion in offspring.
  16. What is gene editing (for example, CRISPR) used for?
    Making targeted DNA changes, such as adding, removing, or replacing genes. Allows precise modifications to specific DNA sequences.
  17. Which term describes an organism that contains DNA from another species?
    Transgenic organism. Foreign DNA is inserted to add new traits.
  18. Which option best describes how selective breeding changes traits: DNA is edited or mating is chosen?
    Mating is chosen; DNA is not directly edited. Selective breeding works through reproduction, not molecular editing.
  19. What is a key difference between selective breeding and genetic engineering?
    Breeding mixes existing genes; engineering directly alters DNA. Breeding works with natural genes; engineering adds new ones.
  20. Which outcome is most likely when a population is genetically uniform due to inbreeding?
    Greater vulnerability to disease or environmental change. Low genetic diversity means fewer defenses against threats.
  21. Identify the key difference between selective breeding and genetic engineering.
    Breeding selects existing variation; engineering directly changes DNA. One works with natural variation, the other creates new genes.
  22. What is genetic variation, and why does selective breeding require it?
    Differences in genes; it provides traits that can be selected. Without different alleles, there's nothing to select for.
  23. Which genetic technology is commonly used to copy a gene many times for study?
    PCR (polymerase chain reaction). Amplifies DNA segments for analysis or experimentation.
  24. Identify the likely result if breeders select only the largest seeds for many generations.
    Average seed size increases in the population. Selecting for a trait shifts the population toward it.
  25. What is the main goal of selective breeding in plants or animals?
    To produce offspring with specific desired traits more often. Breeders select parents with desired traits to pass them on.
  26. What is hybrid vigor (heterosis) most directly associated with?
    Crossbred offspring showing improved growth or health. Mixed genetics often produces healthier offspring than purebreds.
  27. What is hybridization in selective breeding?
    Crossing different varieties to combine desirable traits. Mixing genetic material from different lines creates new combinations.
  28. Identify the most likely result of repeatedly breeding only the highest milk-producing cows.
    Higher average milk production in the herd over generations. Each generation passes on high-production genes more frequently.
  29. What is CRISPR most often used for in genetic technology?
    Precisely editing DNA by cutting and altering specific sequences. A tool that cuts DNA at specific locations.
  30. What is the difference between selective breeding and natural selection?
    Humans choose mates vs. environment favors survival and reproduction. Artificial selection is human-controlled; natural is environment-driven.
  31. What does GMO stand for in life science?
    Genetically modified organism. Organisms with artificially altered genetic material.
  32. Identify the best explanation for why purebred lines may have more inherited disorders.
    Reduced genetic diversity increases expression of harmful recessive alleles. Limited gene pool allows harmful alleles to pair up more often.
  33. What is inbreeding?
    Breeding closely related individuals to increase trait uniformity. Mating relatives concentrates similar alleles in offspring.
  34. Which term describes breeding closely related organisms to keep desired traits?
    Inbreeding. Mating relatives concentrates shared genes, including desired ones.
  35. What is cloning in biology?
    Making a genetically identical copy of an organism or cell. Creates exact genetic duplicates without sexual reproduction.
  36. Identify the genetic technology most suited to turning off one specific gene in an organism.
    Gene editing (such as CRISPR) targeted to that gene. CRISPR can precisely disable specific genes without adding new ones.
  37. Identify the correct statement about gene editing versus selective breeding for speed of change.
    Gene editing can change traits in one generation; breeding takes many. Direct DNA modification is immediate; breeding requires generations.
  38. What is a gene?
    A DNA segment that helps determine a trait. Basic unit of heredity that codes for traits.
  39. Identify the best explanation for why a GMO crop can resist insects.
    It contains a gene that produces an insect-killing protein. The inserted gene codes for a toxin harmful to insects.
  40. What is artificial selection?
    Human-directed selection of traits, rather than natural selection. Humans choose which organisms reproduce, not environmental pressures.

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