Endocytosis, Exocytosis, and Vesicular Trafficking (2A)
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QUESTION
Which motor protein generally moves vesicles toward the microtubule minus end (centrosome)?
QUESTION
What is the naming distinction between v-SNAREs and t-SNAREs?
QUESTION
What is the function of adaptin (AP) complexes in clathrin-mediated endocytosis?
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ANSWER
Link cargo receptors to clathrin by binding sorting motifs in cytosolic tails. Adaptins recognize specific motifs on receptor tails, bridging them to clathrin to ensure selective cargo incorporation into forming vesicles.