What is the correct directionality for writing a nucleic acid sequence by convention?
QUESTION
Which bases are pyrimidines in nucleic acids?
QUESTION
Which atoms are connected by a 3′-5′ phosphodiester linkage in nucleic acids?
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ANSWER
3′-OH of one sugar to 5′ phosphate of the next. The linkage forms between the 3' carbon of one nucleotide's sugar and the 5' phosphate of the adjacent one, creating the backbone.