Psych & Soc Quiz
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FOUNDATIONAL CONCEPT 7: BEHAVIOR AND BEHAVIOR CHANGE
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In a double-blind drug intervention study, healthy adults (n = 48) received either a single dose of a selective D2 receptor antagonist or placebo before completing a probabilistic reversal-learning task that requires updating stimulus–reward associations after contingencies switch. Task-evoked fMRI focused on the dorsal striatum (caudate/putamen), and microdialysis sampling (via an established PET proxy for synaptic dopamine release) was used to estimate task-related dopamine release in the dorsal striatum during the reversal phase. Relative to placebo, the antagonist group showed reduced dorsal striatal dopamine release and committed more perseverative errors (continued choosing the previously rewarded stimulus) after the contingency switch. Which behavior change would be expected following this neurotransmitter modulation, most consistent with the described brain structure involvement?
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