Chem & Physics Quiz
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SCIENTIFIC INQUIRY AND REASONING SKILLS
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A clinician administers a weak acid drug (HA) with pKa=4.0. The stomach is approximated as pH 2 and the blood as pH 7.4. Assume HA (uncharged) crosses membranes readily, while A− does not, and that acid–base equilibrium is rapid. Which interaction between these principles is most likely regarding drug distribution (ion trapping)?
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