Chem & Physics Quiz
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A bacterial enzyme essential for amino acid biosynthesis is targeted by two small molecules. Baseline kinetics: Km=0.40 mMK_m = 0.40\ \text{mM}, Vmax=80 μmol min−1 mg−1V_{max} = 80\ \mu\text{mol}\,\text{min}^{-1}\,\text{mg}^{-1}. Inhibitor D yields Km=0.40 mMK_m = 0.40\ \text{mM} and Vmax=40 μmol min−1 mg−1V_{max} = 40\ \mu\text{mol}\,\text{min}^{-1}\,\text{mg}^{-1}. Inhibitor E yields Km=1.6 mMK_m = 1.6\ \text{mM} and Vmax=80 μmol min−1 mg−1V_{max} = 80\ \mu\text{mol}\,\text{min}^{-1}\,\text{mg}^{-1}. Which statement best describes the effects of inhibitors D and E on enzyme activity?
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