Chem & Physics Quiz
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A cell line was engineered to increase sphingomyelin and cholesterol content in its plasma membrane while keeping total lipid mass constant. Single-particle tracking of a GPI-anchored reporter showed transient confinement to nanometer-scale domains, whereas a non-raft transmembrane reporter showed less confinement. The investigators attributed this to lipid raft formation. Which change is most consistent with the physical basis of raft domains?
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