Chem & Physics Quiz
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A neuron is at rest and receives a brief inhibitory synaptic input that opens ligand-gated Cl−^- channels in the postsynaptic membrane. Typical concentrations are [Cl−]o≫[Cl−]i[\text{Cl}^-]_o \gg [\text{Cl}^-]_i such that EClE_{Cl} is near −70 mV-70\ \text{mV} or slightly more negative. The membrane potential at the time of input is −60 mV-60\ \text{mV}. Based on this scenario, which postsynaptic change is most consistent with opening Cl−^- channels? Assume Cl−^- moves to drive VmV_m toward EClE_{Cl}.
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