Bio & Biochem Quiz
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FOUNDATIONAL CONCEPT 3: ORGAN SYSTEMS AND HOMEOSTASIS
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A cohort study evaluates older adults after a period of prolonged bed rest. Reduced mechanical loading shifts bone remodeling toward osteoclast-mediated resorption, releasing Ca2+ and phosphate (Pi) into plasma and lowering bone mineral density. Calcitonin inhibits osteoclasts when Ca2+ is high, while PTH promotes resorption when Ca2+ is low. If bed rest increases plasma Ca2+ due to increased resorption, which hormonal change is most likely to occur as negative feedback?
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