Bio & Biochem Quiz
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FOUNDATIONAL CONCEPT 3: ORGAN SYSTEMS AND HOMEOSTASIS
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A vascular lab models atherosclerosis by inserting a short, rigid sleeve into a medium-sized artery, reducing the lumen radius in the sleeved segment by 50% without changing blood viscosity. Upstream and downstream segments remain compliant and unchanged. The central physiological principle is that, under laminar flow, resistance is highly sensitive to radius, and local increases in resistance can alter pressure distribution to preserve downstream flow via compensatory mechanisms (homeostasis). Which outcome would be expected at steady state if cardiac output is initially unchanged and no compensatory vasodilation occurs downstream?
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