Bio & Biochem Quiz
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FOUNDATIONAL CONCEPT 3: ORGAN SYSTEMS AND HOMEOSTASIS
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Investigators studied an endocrine axis controlling plasma osmolarity. Participants received an IV infusion of a synthetic analog of a peptide hormone released from the posterior pituitary that increases water reabsorption in the kidney collecting duct. Over 60 minutes, urine flow rate decreased and urine osmolarity increased, while plasma osmolarity fell from 296 to 288 mOsm/kg. Endogenous secretion of the same pituitary hormone was inferred to decrease during the infusion.
Based on the vignette, which outcome is most consistent with peptide hormone action and homeostatic feedback in this axis?
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