Bio & Biochem Quiz
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FOUNDATIONAL CONCEPT 2: CELLS AND CELLULAR ORGANIZATION
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A study tested how changing extracellular K+ affects the resting membrane potential (Vm) of a neuron-like cell line. Cells were permeable to K+ at rest (leak channels), and intracellular K+ was held constant over the short measurement period. The core principle tested is electrochemical gradients and ion diffusion: increasing extracellular K+ reduces the K+ concentration gradient, decreasing net K+ efflux and depolarizing the membrane. Which response would be expected under the given conditions?
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