Bio & Biochem Quiz
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FOUNDATIONAL CONCEPT 1: BIOMOLECULES AND METABOLISM
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To probe translation initiation, investigators compared two capped mRNAs encoding the same reporter protein: one contains a strong Kozak consensus surrounding the AUG start codon, and the other contains multiple mismatches in the Kozak sequence. Equal mRNA amounts were transfected into cells, and mRNA stability was similar. Which outcome is most consistent with the role of the Kozak sequence in eukaryotic translation initiation?
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