Bio & Biochem Quiz
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FOUNDATIONAL CONCEPT 1: BIOMOLECULES AND METABOLISM
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A mechanistic description focuses on 3' end processing of an mRNA encoding an insulin-responsive transporter. A point mutation disrupts the AAUAAA polyadenylation signal but leaves the coding region intact. In mutant cells, nuclear RNA accumulates as a longer transcript that extends beyond the normal 3' end, and cytosolic mRNA levels drop.
Which outcome would be expected from this mutation?
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