Hormone Transport, Receptors, Signal Transduction (3A)
Bio & Biochem · Flashcards
BIO & BIOCHEM · FLASHCARDS
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QUESTION
What is the primary receptor location for peptide hormones in target cells?
QUESTION
What is the major effect of plasma protein binding on steroid hormone half-life?
QUESTION
What is the typical downstream signaling consequence of RTK phosphotyrosines?
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ANSWER
Docking of SH2/PTB proteins to initiate kinase cascades. Phosphotyrosine residues on activated RTKs recruit SH2/PTB domain proteins, which propagate signals through pathways like MAPK for cell growth.