Cancer Biology and Loss of Cell Cycle Control (2C)
Bio & Biochem · Flashcards
BIO & BIOCHEM · FLASHCARDS
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QUESTION
What is a tumor suppressor gene?
QUESTION
Identify the term for cancer cell growth without attachment to a surface or matrix.
QUESTION
What is the key role of p21 in cell cycle control?
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ANSWER
Cyclin-dependent kinase inhibitor that enforces
G
1
G_1
G
1
arrest. p21 blocks cyclin-CDK activity to prevent progression from
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1
G_1
G
1
to S phase during stress.
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