What is RNA interference (RNAi) in the context of post-transcriptional gene regulation?
QUESTION
What enzyme class adds acetyl groups to histone tails to promote transcription?
QUESTION
What is the direct effect of histone acetylation on chromatin structure?
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ANSWER
Decreases histone-DNA affinity, opening chromatin. Acetyl groups reduce the electrostatic attraction between histones and DNA, promoting a more open structure for gene activation.