Genetics Quiz
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GENE REGULATION
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The expression of gene Z is regulated by two transcription factors: TF-Alpha (an activator) and TF-Beta (a repressor). They bind to adjacent, non-overlapping sites in the gene's promoter. High expression of gene Z requires TF-Alpha to be bound and TF-Beta to be unbound. In a specific cell line, a mutation renders TF-Alpha completely unable to bind DNA. Simultaneously, an experimental condition reduces the cellular concentration of TF-Beta by 50%. What is the predicted change in the transcription of gene Z?
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