Genetics Quiz
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GENE REGULATION
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The PABPC1 protein binds to the poly(A) tail of eukaryotic mRNAs and also interacts with the eIF4G translation initiation factor at the 5' cap. This closed-loop structure is thought to enhance translation. A mutation in PABPC1 that prevents its interaction with eIF4G but still allows poly(A) binding would most likely lead to which direct consequence?
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