Genetics Quiz
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MENDELIAN GENETICS
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In a study of bone health in mice, researchers conducted a genome-wide scan and identified a significant Quantitative Trait Locus (QTL) on chromosome 5 associated with variation in femur length. In a separate analysis of the same mice, they found that a QTL for serum phosphate level also mapped to the exact same location on chromosome 5. Subsequent fine-mapping and sequencing revealed that a single gene, Enpp1, within this locus has variants that affect both traits. This discovery provides strong evidence for which genetic principle?
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