Genetics Quiz
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DNA REPLICATION, REPAIR & MUTATION
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In an E. coli cell that is deficient in Dam methyltransferase, the mismatch repair (MMR) system cannot reliably distinguish the parental and daughter strands. If a G-T mismatch occurs due to a replication error (where T was incorrectly incorporated opposite a G on the template strand), and the MMR system incorrectly identifies the G-containing parental strand as the one to be repaired, what will be the ultimate outcome for the DNA sequence at this position after another round of replication?
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