Treatment Matching - Eppp Knowledge

1. Which treatment is evidence-based for acute mania requiring rapid symptom control?

   Mood stabilizer and/or antipsychotic medication (pharmacotherapy first-line). Pharmacotherapy is prioritized for acute mania due to its rapid efficacy in stabilizing mood and reducing severe symptoms when immediate control is necessary.

2. Which treatment is first-line for disruptive behavior disorders when caregiver involvement is feasible?

   Behavioral parent training (BPT) / parent management training. BPT is supported by strong evidence for disruptive behaviors as it equips parents with strategies to reinforce positive behaviors and manage defiance effectively.

3. Which evidence-based psychotherapy is first-line for PTSD when trauma-focused care is indicated?

   Trauma-focused CBT (e.g., prolonged exposure or cognitive processing therapy). These therapies are empirically validated for PTSD by processing traumatic memories and challenging maladaptive cognitions related to the trauma.

4. Which psychotherapy is first-line for panic disorder and agoraphobia based on strongest evidence?

   Cognitive-behavioral therapy with interoceptive and situational exposure. It has the strongest empirical support for reducing panic symptoms by systematically exposing clients to feared bodily sensations and avoided situations.

5. Which psychotherapy is first-line for severe behavioral dyscontrol and emotion dysregulation in adolescents?

   Dialectical behavior therapy for adolescents (DBT-A). DBT-A is adapted for adolescents and supported by evidence for improving emotion regulation and reducing self-harm in those with severe behavioral issues.

6. Which intervention is most evidence-based for alcohol use disorder with ambivalence about change?

   Motivational interviewing (MI) / motivational enhancement therapy. MI is supported by evidence for alcohol use disorder as it resolves ambivalence by enhancing intrinsic motivation for change through empathetic, collaborative dialogue.

7. What evidence-based treatment is first-line for obsessive-compulsive disorder (OCD)?

   Exposure and response prevention (ERP). ERP is supported by robust evidence for OCD as it targets obsessions and compulsions through exposure while preventing ritualistic responses.

8. Which treatment is most evidence-based for autism-related irritability/aggression when severe and persistent?

   Atypical antipsychotic medication (risperidone or aripiprazole) plus behavioral supports. Atypical antipsychotics are FDA-approved for severe autism-related irritability, with behavioral supports enhancing overall management and skill development.

9. Which evidence-based psychotherapy is first-line for social anxiety disorder?

   CBT with exposure and cognitive restructuring. This approach is supported by strong evidence for social anxiety as it combines behavioral exposure to social situations with cognitive techniques to reframe anxious thoughts.

10. Which evidence-based psychotherapy is first-line for insomnia disorder when medication is not preferred?

    Cognitive-behavioral therapy for insomnia (CBT-I). CBT-I is empirically supported for insomnia as it targets maladaptive sleep habits and cognitions without the risks associated with long-term medication use.

11. Which psychosocial treatment is evidence-based for stimulant use disorder (e.g., cocaine, methamphetamine)?

    Contingency management. Contingency management is evidence-based for stimulant use as it uses positive reinforcement to promote abstinence and adherence to treatment goals.

12. Which psychotherapy is first-line for binge-eating disorder based on strongest evidence?

    CBT (often CBT-E or manualized CBT for BED). CBT approaches are evidence-based for BED as they help interrupt binge cycles by targeting cognitive distortions and building coping skills for emotional triggers.

13. Which evidence-based psychotherapy is first-line for generalized anxiety disorder (GAD)?

    CBT (worry exposure, cognitive therapy, and relaxation/skills training). CBT for GAD is evidence-based as it addresses excessive worry through exposure, cognitive restructuring, and relaxation to reduce anxiety symptoms.

14. Which treatment is most evidence-based for specific phobia in an otherwise stable adult?

    In vivo exposure therapy. In vivo exposure is empirically validated for specific phobias by gradually confronting the feared object or situation to extinguish conditioned fear responses.

15. Which psychosocial treatment is evidence-based for persistent psychotic symptoms despite medication?

    CBT for psychosis (CBTp). CBTp is evidence-based for persistent psychosis as it helps normalize experiences and challenge delusional beliefs without directly confronting their validity.

16. Which psychotherapy is first-line for schizophrenia to reduce relapse when combined with medication?

    Family psychoeducation (family intervention). Family psychoeducation is supported by evidence for schizophrenia as it educates families on illness management, reducing stress and relapse rates alongside pharmacotherapy.

17. Which family-based treatment is first-line for adolescent anorexia nervosa?

    Family-based treatment (FBT; Maudsley model). FBT is empirically validated for adolescent anorexia as it empowers families to restore weight and normalize eating without focusing on underlying causes initially.

18. Which psychotherapy is most evidence-based for borderline personality disorder with self-harm risk?

    Dialectical behavior therapy (DBT). DBT is empirically supported for BPD with self-harm as it teaches emotion regulation, distress tolerance, and interpersonal skills to reduce risky behaviors.

19. Which psychotherapy is first-line for major depressive disorder with clear interpersonal precipitants?

    Interpersonal psychotherapy (IPT). IPT is evidence-based for MDD with interpersonal triggers as it focuses on resolving role disputes, transitions, grief, and deficits to alleviate depression.

20. Which psychotherapy is first-line for bulimia nervosa in adults based on best evidence?

    CBT-Enhanced (CBT-E). CBT-E is supported by robust evidence for bulimia as it addresses dysfunctional cognitions about body image and eating behaviors through structured interventions.

21. Identify the best first-line treatment for childhood enuresis when no medical cause is found.

    Urine alarm (enuresis alarm) with behavioral support. Urine alarms are evidence-based for enuresis as they condition arousal to bladder signals, effectively reducing bedwetting with behavioral reinforcement.

22. Which psychotherapy is evidence-based as an adjunct for bipolar disorder to reduce relapse?

    Interpersonal and social rhythm therapy (IPSRT). IPSRT is empirically supported as an adjunct for bipolar disorder by stabilizing daily routines and social rhythms to prevent mood episode triggers.

23. Which option best matches client factors to treatment: high suicide risk and BPD traits?

    DBT with structured suicide risk management and skills coaching. DBT matches high suicide risk in BPD by providing comprehensive skills training, risk assessment, and crisis intervention to enhance safety and emotion regulation.

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