College Chemistry Quiz
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ACIDS, BASES & AQUEOUS EQUILIBRIA
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An analytical chemist needs to choose between two buffer systems for maintaining pH 8.5 ± 0.1 during a protein purification procedure. System A: Tris buffer (pKa=8.1) at 0.10 M total concentration. System B: Glycine buffer (pKa=9.6) at 0.25 M total concentration. Which system would provide better pH control at the target pH?
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