Cell Biology Quiz
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MEMBRANES AND TRANSPORT
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In a comparative study of bacterial and mammalian cells, researchers find that bacterial amino acid uptake is completely blocked by CCCP (a protonophore that dissipates proton gradients) but unaffected by ouabain. In contrast, mammalian amino acid uptake is blocked by ouabain but unaffected by CCCP. Both cell types show reduced amino acid uptake when ATP synthesis is inhibited, but the time course differs: bacterial uptake decreases gradually over 15 minutes while mammalian uptake decreases gradually over 5 minutes. What accounts for these differences?
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