Cell Biology Quiz
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CELL STRUCTURE AND ORGANELLES
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A research team creates cells that express only mitochondrial-targeted Bcl-2 (no cytosolic Bcl-2) and cells that express only cytosolic Bcl-2 (no mitochondrial Bcl-2). When both cell types are exposed to DNA damage, the mitochondrial Bcl-2 cells show strong resistance to apoptosis, while cytosolic Bcl-2 cells show weak resistance. What does this suggest about Bcl-2's mechanism of action?
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