Technological Advances/Limitations: Disease After 1900 - AP World History

  1. What medical imaging technology became widespread after World War II?
    X-rays. Discovered in 1895, became standard diagnostic tool post-WWII.
  2. Identify the vector responsible for transmitting malaria.
    Anopheles mosquito. Female mosquito transmits malaria parasites through bites.
  3. Which disease outbreak in 2014 highlighted the importance of rapid response?
    Ebola. West African outbreak demonstrated need for global preparedness.
  4. What is the primary role of the Centers for Disease Control and Prevention (CDC)?
    Protect public health. US federal agency monitoring and preventing disease outbreaks.
  5. What is the goal of the Global Polio Eradication Initiative?
    Eradicate polio. Worldwide campaign to eliminate polio through vaccination.
  6. Identify one advantage of point-of-care testing in disease diagnosis.
    Immediate results. Rapid testing enables quick diagnosis and treatment decisions.
  7. Identify the first vaccine developed using mRNA technology.
    COVID-19 vaccine. Pfizer-BioNTech and Moderna vaccines used mRNA technology.
  8. What is the primary method to prevent the spread of vector-borne diseases?
    Vector control. Eliminates mosquitoes and other disease-carrying organisms.
  9. What was one major limitation of antibiotics discovered after 1900?
    Antibiotic resistance. Overuse led to bacteria evolving resistance mechanisms.
  10. What is the main purpose of quarantine as a public health measure?
    Prevent disease spread. Isolates infected individuals to break transmission chains.
  11. What technological advance enabled mass production of vaccines post-1900?
    Recombinant DNA technology. Allows genetic engineering of vaccine components in labs.
  12. Identify the primary goal of the Human Genome Project completed in 2003.
    Map all human genes. Identified genetic basis for many diseases and treatments.
  13. What is one significant limitation of vaccines discovered for viral diseases?
    Mutating viruses. Viruses change genetic structure, making vaccines less effective.
  14. Identify the disease eradicated by the Global Smallpox Eradication Program.
    Smallpox. Eradicated through global vaccination campaign by 1980.
  15. Identify a major limitation of monoclonal antibodies in disease treatment.
    High cost. Expensive production limits widespread therapeutic use.
  16. What was a major public health achievement in the 20th century related to water?
    Water fluoridation. Dramatically reduced tooth decay and dental disease globally.
  17. Identify the first disease for which a vaccine was developed using recombinant DNA technology.
    Hepatitis B. First genetically engineered vaccine approved in 1986.
  18. What is the primary advantage of personalized medicine in disease treatment?
    Tailored treatments. Uses genetic information to customize individual patient care.
  19. Which disease was significantly reduced by the introduction of insecticide-treated nets?
    Malaria. Nets protect sleeping individuals from infected mosquitoes.
  20. What is one challenge of global health initiatives post-1900?
    Resource allocation. Limited funding creates inequitable access to healthcare.
  21. What is the primary function of antiviral drugs?
    Inhibit viral replication. Blocks viral reproduction within infected cells.
  22. Which pandemic in 1918 led to millions of deaths worldwide?
    The Spanish flu. H1N1 influenza killed 50-100 million people globally.
  23. Which pandemic in the late 20th century highlighted the need for global health cooperation?
    HIV/AIDS. Required unprecedented international collaboration and research.
  24. Identify the organization responsible for declaring global health emergencies.
    World Health Organization (WHO). UN agency with authority to coordinate international health responses.
  25. What is the primary advantage of telemedicine in disease management?
    Remote patient care. Provides medical care without geographic barriers.
  26. What is the key advantage of mRNA vaccines introduced in the 21st century?
    Rapid development. Can be designed and produced much faster than traditional vaccines.
  27. Identify the first antiviral drug approved for the treatment of HIV/AIDS.
    AZT (Zidovudine). First drug to slow HIV progression, approved in 1987.
  28. What is a major challenge in combating emerging infectious diseases after 1900?
    Rapid pathogen mutation. Pathogens evolve faster than treatment development.
  29. Identify the technology that allowed for the rapid sequencing of viral genomes.
    Next-generation sequencing. High-speed DNA sequencing enables rapid pathogen identification.
  30. Identify a key benefit of digital health technologies in managing diseases.
    Real-time data collection. Enables immediate tracking and response to disease outbreaks.
  31. What is the role of public health campaigns in disease prevention post-1900?
    Educate and promote health practices. Inform populations about prevention and healthy behaviors.
  32. Which institution was founded in 1948 to address global health issues?
    World Health Organization (WHO). International body coordinating global health responses.
  33. Which disease saw a resurgence due to vaccine hesitancy in the 21st century?
    Measles. Declining vaccination rates led to increased outbreaks.
  34. Which disease was declared eradicated worldwide in 1980?
    Smallpox. Last naturally occurring case reported in Somalia, 1977.
  35. Which medical advancement has improved early detection of diseases post-1900?
    Diagnostic imaging. CT, MRI, and ultrasound detect diseases before symptoms appear.
  36. Which disease was targeted by the first successful vaccine developed by Jonas Salk?
    Polio. First successful vaccine against paralytic disease in 1955.
  37. What was the impact of penicillin's discovery on infectious diseases?
    Penicillin revolutionized bacterial infection treatment. First widely effective antibiotic, saving millions of lives.
  38. What is the primary focus of epidemiological studies after 1900?
    Disease distribution and determinants. Studies patterns, causes, and control of disease spread.

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