AP Biology Quiz
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Two groups of genetically identical tadpoles are reared in water with either high or low thyroid hormone (TH). Tadpoles in high TH develop hind limbs earlier and show increased expression of TH-responsive genes in limb bud cells; sequencing shows no differences in those genes. When high-TH tadpoles are moved to low TH, the rate of limb development slows. Which explanation best accounts for the hormone-dependent differences in limb development timing?
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