AP Biology Quiz
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GENE EXPRESSION AND REGULATION
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A biologist adds a drug that specifically inhibits helicase in rapidly dividing cells. In untreated cells, helicase separates the parental DNA strands at replication origins, allowing DNA polymerase to copy each template strand using complementary base pairing. After drug treatment, the biologist measures incorporation of labeled deoxyribonucleotides into DNA and finds a large decrease. Which explanation best accounts for the decreased nucleotide incorporation in treated cells?
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