Anatomy and Physiology Quiz
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A researcher studying calcium regulation discovers a compound that specifically blocks calcium release from the sarcoplasmic reticulum without affecting extracellular calcium entry. When this compound is applied to different muscle types, she observes that skeletal muscle contraction is completely abolished, cardiac muscle contraction is severely reduced but not eliminated, and smooth muscle contraction is only mildly affected. What difference in calcium handling mechanisms best explains this pattern of effects?
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