Thermoregulation and Skin Functions - Anatomy and Physiology

  1. What makes the skin a barrier against water loss?
    Keratinized cells and lipids in the stratum corneum and stratum granulosum block water from escaping.
  2. What role does the skin play in vitamin D production?
    UVB light converts 7-dehydrocholesterol in the skin to cholecalciferol (vitamin D3), which the liver and kidneys then activate.
  3. Which mechanism accounts for most heat loss from a resting person in a cool room?
    Radiation of infrared energy from the skin to cooler surroundings.
  4. What are the four physical mechanisms by which the skin loses heat?
    Radiation, conduction, convection, and evaporation.
  5. How does the hypodermis contribute to temperature regulation?
    Its adipose tissue insulates the body and reduces heat loss to the surroundings.
  6. How do dermal blood vessels help release excess heat?
    They dilate, bringing more warm blood close to the skin surface so heat can leave the body.
  7. What is the acid mantle of the skin?
    The slightly acidic film on the skin surface (pH around 5) that inhibits the growth of many microbes.
  8. A breeze cools dry skin faster than still air at the same temperature. Which heat-loss mechanism is increased?
    Convection, because moving air carries warmed air away from the skin surface.
  9. How does melanin protect the skin?
    It absorbs ultraviolet radiation, protecting the DNA of keratinocytes from UV damage.
  10. Air temperature is 40 °C, above skin temperature. Which heat-loss mechanism can still remove heat from the body?
    Evaporation of sweat. Radiation, conduction and convection add heat when the surroundings are warmer than the skin.
  11. Which sweat glands are the main source of sweat for heat loss?
    Eccrine (merocrine) sweat glands, found over most of the body surface.

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