Somatosensation: Touch, Pain, Temperature - Anatomy and Physiology

  1. Which receptors detect deep pressure and high-frequency vibration?
    Lamellated (Pacinian) corpuscles, which are rapidly adapting and lie deep in the dermis and hypodermis.
  2. A patient with myocardial ischemia reports pain. Where is this pain commonly referred?
    To the left arm, shoulder, chest wall or jaw, which share spinal segments (about T1 to T4) with the heart.
  3. What is the difference between phasic and tonic receptors?
    Phasic receptors adapt quickly and signal changes in a stimulus; tonic receptors adapt slowly and signal a sustained stimulus.
  4. Which slowly adapting receptors in the basal epidermis signal sustained light touch and texture?
    Tactile (Merkel) discs, formed by Merkel cells and their nerve endings.
  5. Which receptors detect light touch in hairless skin and lie in the dermal papillae?
    Tactile (Meissner) corpuscles, which are rapidly adapting.
  6. Which receptor type detects pain and most temperature changes?
    Free nerve endings, which serve as nociceptors and thermoreceptors.
  7. Which slowly adapting receptors in the dermis respond to skin stretch?
    Bulbous (Ruffini) endings.
  8. Which fibers carry fast, sharp pain, and which carry slow, dull, burning pain?
    Fast sharp pain: thinly myelinated A-delta fibers. Slow burning pain: unmyelinated C fibers.
  9. What is referred pain?
    Visceral pain perceived at a skin region, because both share spinal cord segments that converge on the same neurons.
  10. Why is two-point discrimination finest on the fingertips and lips?
    These areas have a high density of receptors with small receptive fields.
  11. What is a receptive field of a sensory neuron?
    The area of skin whose stimulation changes that neuron's activity. Smaller fields allow finer localization.
  12. What is a receptor (generator) potential?
    A graded depolarization of a sensory ending whose size varies with stimulus strength; large enough ones trigger action potentials.

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