Skin Layers and Accessory Structures - Anatomy and Physiology

  1. Which epidermal layer contains the dividing stem cells that renew the epidermis?
    The stratum basale (stratum germinativum), the deepest layer, resting on the basement membrane.
  2. What are the two layers of the dermis and their tissue types?
    The papillary layer (areolar connective tissue) and the deeper reticular layer (dense irregular connective tissue).
  3. How do apocrine sweat glands differ from eccrine sweat glands?
    Apocrine glands lie in the axillary and anogenital regions, empty into hair follicles and become active at puberty; eccrine glands open directly onto the skin.
  4. How do living cells of the epidermis receive nutrients?
    By diffusion from blood vessels in the dermis, because the epidermis is avascular.
  5. Which part of the nail produces new nail cells for growth?
    The nail matrix, located at the proximal end beneath the nail fold.
  6. List the layers of the epidermis of thick skin from deepest to most superficial.
    Stratum basale, spinosum, granulosum, lucidum, and corneum.
  7. Where is the stratum lucidum found?
    Only in thick skin, such as the palms of the hands and soles of the feet.
  8. What does the arrector pili muscle do?
    It is smooth muscle that pulls the hair follicle upright, producing goosebumps.
  9. What makes up the stratum corneum?
    Many layers of dead, flattened, keratin-filled cells that protect against abrasion, water loss and microbes.
  10. What is the role of Langerhans (epidermal dendritic) cells?
    They are immune cells that capture antigens in the epidermis and present them to lymphocytes.
  11. Where do sebaceous glands usually release their secretion?
    Into hair follicles. Sebum lubricates hair and skin and slows water loss.
  12. Which epidermal cells produce melanin, and where do they pass it?
    Melanocytes in the stratum basale. They transfer melanin to nearby keratinocytes, where it shields the nucleus from UV light.

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