Motility and Regulation (Peristalsis, Hormones) - Anatomy and Physiology

  1. Which hormone released by the duodenum in response to fats and proteins stimulates gallbladder contraction?
    Cholecystokinin (CCK). It also stimulates pancreatic enzyme secretion and slows gastric emptying.
  2. What is the enterogastric reflex?
    Distension, acid or fat in the duodenum inhibits gastric motility and emptying, so the small intestine is not overloaded.
  3. Which enteric nerve plexus mainly controls GI motility?
    The myenteric (Auerbach) plexus, located between the circular and longitudinal muscle layers.
  4. How does parasympathetic (vagal) stimulation affect GI motility and secretion?
    It increases both. Sympathetic stimulation generally decreases motility and secretion.
  5. What is segmentation in the small intestine?
    Rhythmic contraction of nonadjacent segments of circular muscle that mixes chyme with secretions, with little forward movement.
  6. Which enteric nerve plexus mainly regulates glandular secretion and local blood flow?
    The submucosal (Meissner) plexus, located in the submucosa.
  7. Which hormone from stomach G cells stimulates gastric acid secretion and gastric motility?
    Gastrin.
  8. Which cells act as pacemakers that generate the slow waves of GI smooth muscle?
    The interstitial cells of Cajal.
  9. What is peristalsis?
    Waves of alternating contraction and relaxation of the muscularis that propel contents along the digestive tract.
  10. What is the gastrocolic reflex?
    Food entering the stomach triggers mass movements in the colon, often producing an urge to defecate after a meal.
  11. What is the migrating motor complex, and when does it occur?
    A cycle of strong contractions during fasting that sweeps undigested residue and bacteria from the small intestine toward the colon.
  12. Which hormone released by the duodenum in response to acid stimulates bicarbonate-rich pancreatic secretion?
    Secretin. The bicarbonate neutralizes acidic chyme entering the duodenum.

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