Male Reproductive Anatomy and Spermatogenesis - Anatomy and Physiology

  1. Which cells form the blood-testis barrier and nourish developing sperm under the influence of FSH?
    Sustentocytes (Sertoli cells), joined by tight junctions inside the seminiferous tubules.
  2. How many spermatozoa result from one primary spermatocyte?
    Four. Meiosis I gives two secondary spermatocytes, and meiosis II gives four spermatids that mature into sperm.
  3. Why are the testes located in the scrotum outside the abdominal cavity?
    Viable sperm production requires a temperature about 3 degrees C below core body temperature.
  4. In which duct do sperm mature, gain the ability to swim and get stored?
    The epididymis.
  5. Which cell division converts a primary spermatocyte into two secondary spermatocytes?
    Meiosis I, which reduces the cells from diploid to haploid.
  6. Which accessory gland surrounds the urethra just below the bladder and secretes a milky fluid containing PSA and citrate?
    The prostate gland.
  7. After leaving the epididymis, which duct carries sperm up through the inguinal canal toward the ejaculatory duct?
    The ductus (vas) deferens. It joins the duct of the seminal vesicle to form the ejaculatory duct.
  8. Where in the testis does spermatogenesis take place?
    In the seminiferous tubules.
  9. What is spermiogenesis?
    The maturation of spermatids into sperm without division: the Golgi forms the acrosome, a flagellum grows and excess cytoplasm is shed.
  10. Which testicular cells produce testosterone in response to LH?
    Interstitial (Leydig) cells, located between the seminiferous tubules.
  11. Which accessory gland contributes the largest share of semen volume, including fructose for sperm energy?
    The seminal vesicles, which provide most of the semen volume.
  12. Which hormone do Sertoli cells secrete to reduce FSH release?
    Inhibin, which acts by negative feedback on the anterior pituitary.

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