Major Endocrine Glands and Core Hormones - Anatomy and Physiology

  1. Which glands secrete the main hormone that raises blood calcium?
    The parathyroid glands, which secrete parathyroid hormone (PTH).
  2. Which hormones does the adrenal medulla secrete?
    Epinephrine and norepinephrine, mostly epinephrine, released in response to sympathetic stimulation.
  3. Which zone of the adrenal cortex secretes most of the body's cortisol?
    The zona fasciculata, the middle zone of the adrenal cortex.
  4. A patient has hyperthyroidism caused by antibodies that stimulate the TSH receptor. What is the disorder?
    Graves disease. The antibodies mimic TSH, so the thyroid oversecretes T3 and T4.
  5. Which gland secretes melatonin?
    The pineal gland. Melatonin secretion rises in darkness and helps regulate circadian rhythms.
  6. Which zone of the adrenal cortex secretes aldosterone?
    The zona glomerulosa, the outermost zone of the adrenal cortex.
  7. Which hormones do the follicular cells of the thyroid gland secrete?
    Thyroxine (T4) and triiodothyronine (T3), which raise basal metabolic rate.
  8. Which pancreatic islet cells secrete insulin?
    Beta cells. Insulin lowers blood glucose by promoting glucose uptake and storage.
  9. Which hormone do the kidneys secrete in response to low blood oxygen?
    Erythropoietin (EPO), which stimulates red blood cell production in the red bone marrow.
  10. Which hormone do the atria of the heart secrete when stretched by high blood volume?
    Atrial natriuretic peptide (ANP), which promotes sodium and water excretion and lowers blood pressure.
  11. Which thyroid cells secrete calcitonin, and what does it do?
    Parafollicular (C) cells. Calcitonin lowers blood calcium, mainly by inhibiting osteoclasts.
  12. Which pancreatic islet cells secrete glucagon?
    Alpha cells. Glucagon raises blood glucose by stimulating glycogenolysis and gluconeogenesis in the liver.

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