Kidney Anatomy and Nephron Structure - Anatomy and Physiology

  1. Order these structures as urine drains from a renal papilla: renal pelvis, major calyx, ureter, minor calyx.
    Minor calyx, major calyx, renal pelvis, ureter.
  2. What are the two main parts of a nephron?
    The renal corpuscle (glomerulus plus glomerular capsule) and the renal tubule.
  3. Which cells of the juxtaglomerular apparatus secrete renin, and where are they located?
    Granular (juxtaglomerular) cells, modified smooth muscle cells in the wall of the afferent arteriole.
  4. Order these segments as filtrate leaves the glomerular capsule: DCT, nephron loop, collecting duct, PCT.
    PCT, nephron loop, DCT, then collecting duct. The collecting duct receives filtrate from many nephrons.
  5. What cells form the visceral layer of the glomerular capsule?
    Podocytes. Their foot processes wrap the glomerular capillaries and leave filtration slits between them.
  6. Where are the kidneys located relative to the peritoneum?
    Retroperitoneal: behind the parietal peritoneum, against the posterior abdominal wall.
  7. Which arteriole carries blood into the glomerulus, and which carries it out?
    The afferent arteriole carries blood in; the efferent arteriole carries it out.
  8. How do juxtamedullary nephrons differ structurally from cortical nephrons?
    Their glomeruli lie near the cortex-medulla junction and their nephron loops dip deep into the medulla; most nephrons are cortical with short loops.
  9. What capillaries arise from the efferent arterioles of juxtamedullary nephrons and run beside their long loops?
    The vasa recta. Efferent arterioles of cortical nephrons instead feed the peritubular capillaries.
  10. Which nephron segment has cells with a dense microvillus brush border?
    The proximal convoluted tubule. Its large surface area suits it for reabsorbing most of the filtrate.
  11. Which renal arteries lie between the interlobar arteries and the cortical radiate arteries?
    The arcuate arteries, which arch along the boundary between the cortex and the medulla.
  12. What are the two main regions of kidney tissue, from outer to inner?
    The renal cortex on the outside and the renal medulla inside, which is divided into cone-shaped renal pyramids.

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