Heart Anatomy and Cardiac Cycle - Anatomy and Physiology

  1. Why is the wall of the left ventricle much thicker than that of the right ventricle?
    The left ventricle pumps blood into the systemic circuit, against much higher pressure and resistance than the pulmonary circuit.
  2. When does the mitral valve open during the cardiac cycle?
    When left ventricular pressure falls below left atrial pressure at the end of isovolumetric relaxation, which begins ventricular filling.
  3. When does the aortic valve open during the cardiac cycle?
    When left ventricular pressure rises above aortic pressure, which begins the ejection phase.
  4. Where do the coronary arteries arise?
    From the base of the ascending aorta, just above the aortic valve.
  5. Which valve lies between the right atrium and the right ventricle?
    The tricuspid valve.
  6. At rest, how does most ventricular filling occur?
    Passively during ventricular diastole, before the atria contract; atrial systole adds only the final portion (roughly 20 to 30 percent).
  7. The fossa ovalis in the interatrial septum is a remnant of which fetal structure?
    The foramen ovale, which let blood pass from the right atrium to the left atrium in the fetus.
  8. Which valve lies between the left atrium and the left ventricle?
    The mitral (bicuspid) valve.
  9. What event produces the first heart sound (S1)?
    Closure of the atrioventricular (tricuspid and mitral) valves at the start of ventricular systole.
  10. What event produces the second heart sound (S2)?
    Closure of the semilunar (aortic and pulmonary) valves at the start of ventricular diastole.
  11. What is the state of the heart valves during isovolumetric contraction?
    All four valves are closed, so ventricular pressure rises while ventricular volume stays constant.
  12. Which structures prevent the atrioventricular valve cusps from everting into the atria during ventricular contraction?
    The chordae tendineae, anchored to papillary muscles that tense as the ventricle contracts.

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