Fertilization and Early Development - Anatomy and Physiology

  1. What happens during the acrosome reaction?
    The acrosome releases enzymes that digest a path through the zona pellucida so the sperm can reach the oocyte membrane.
  2. What does sperm entry trigger in the secondary oocyte?
    Completion of meiosis II, producing the ovum and a second polar body.
  3. Which part of the blastocyst gives rise to the embryo itself?
    The inner cell mass (embryoblast).
  4. What is cleavage in early development?
    Rapid mitotic divisions of the zygote without overall growth, so the cells (blastomeres) become smaller with each division.
  5. Which trophoblast layer invades the endometrium during implantation?
    The syncytiotrophoblast, a multinucleated layer that digests its way into the uterine wall.
  6. What does gastrulation produce?
    The three primary germ layers: ectoderm, mesoderm, and endoderm.
  7. About how many days after fertilization does implantation begin?
    About 6 to 7 days after fertilization, when the blastocyst attaches to the endometrium.
  8. What is a morula?
    A solid ball of about 16 or more blastomeres, reached about 3 to 4 days after fertilization.
  9. Which part of the blastocyst gives rise to the fetal portion of the placenta?
    The trophoblast, which forms the chorion.
  10. From which primary germ layer does the nervous system develop?
    Ectoderm, which also forms the epidermis.
  11. What is capacitation?
    The changes sperm undergo in the female tract, including loss of membrane cholesterol, that make them able to undergo the acrosome reaction and fertilize.
  12. What is the cortical reaction, and what does it prevent?
    Cortical granules release enzymes that alter the zona pellucida after sperm entry, blocking polyspermy (entry of additional sperm).

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