Exercise Physiology: Acute Responses - Anatomy and Physiology

  1. Roughly how much does cardiac output rise from rest to maximal exercise in a healthy untrained adult?
    About four- to fivefold, from about 5 L/min at rest to about 20 to 25 L/min.
  2. During exercise, oxygen consumption is 1500 mL/min and the arteriovenous O2 difference is 15 mL O2 per 100 mL blood. What is cardiac output?
    10 L/min. By the Fick principle, cardiac output = 1500 mL/min divided by 150 mL O2 per liter of blood.
  3. What is the lactate threshold?
    The exercise intensity at which blood lactate begins to rise sharply because production exceeds clearance.
  4. How does the arteriovenous oxygen difference change during exercise?
    It widens, because active muscle extracts a larger share of the oxygen from each volume of blood.
  5. During dynamic exercise such as running, how do systolic and diastolic blood pressure change?
    Systolic pressure rises substantially, while diastolic pressure stays about the same or falls slightly because active muscle vessels dilate.
  6. During intense exercise, which abdominal organs receive markedly reduced blood flow?
    The digestive organs and the kidneys, through sympathetic vasoconstriction, freeing blood for active muscle.
  7. Which local chemical changes in active skeletal muscle cause its arterioles to dilate?
    Increased CO2, H+, K+, and adenosine, decreased O2, and higher temperature.
  8. During moderate exercise, how does minute ventilation mainly increase at first?
    Mainly through a larger tidal volume; breathing rate rises more as intensity increases.
  9. What causes heart rate to rise within seconds of starting exercise, before metabolites accumulate?
    Withdrawal of parasympathetic (vagal) tone and central command from the brain, followed by sympathetic activation.
  10. How does total peripheral resistance change during dynamic whole-body exercise?
    It decreases, because metabolic vasodilation in active skeletal muscle outweighs vasoconstriction elsewhere.
  11. How does stroke volume respond as exercise intensity increases?
    It rises, from greater venous return (muscle pump) and sympathetic contractility, then plateaus at moderate intensity in most people.

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