Endocrine vs Neural Control - Anatomy and Physiology

  1. How does each system carry its signal to target cells: neural control versus endocrine control?
    Neural: electrical impulses along axons, then neurotransmitter across a synapse. Endocrine: hormones carried by the blood.
  2. Over what distance does a neurotransmitter act, compared with a hormone?
    A neurotransmitter crosses only a narrow synaptic cleft (tens of nanometers); a hormone travels through the bloodstream to targets anywhere in the body.
  3. Norepinephrine is released by a sympathetic nerve ending onto a target and also by the adrenal medulla into blood. How is it classified in each case?
    As a neurotransmitter at the nerve ending and as a hormone when released into blood. The classification depends on delivery route, not the molecule.
  4. What determines which cells respond to a neural signal?
    Anatomical connection: only the cells that a neuron synapses with receive its neurotransmitter.
  5. How does the nervous system encode signal strength, compared with the endocrine system?
    The nervous system uses the frequency of action potentials; the endocrine system uses the concentration of hormone in the blood.
  6. What are neurons that release hormones into the blood called, and what is a classic example?
    Neurosecretory (neuroendocrine) cells, such as hypothalamic neurons that release ADH and oxytocin from the posterior pituitary.
  7. What determines which cells respond to a circulating hormone?
    Whether the cells have specific receptors for that hormone. Every cell is exposed, but only cells with the receptor respond.
  8. Which endocrine gland is a modified sympathetic ganglion that releases epinephrine into the blood?
    The adrenal medulla.
  9. Which control system, neural or endocrine, typically produces longer-lasting effects?
    Endocrine control. Hormone effects can persist for minutes to days, while neural effects usually stop soon after stimulation ends.
  10. Which control system, neural or endocrine, has the faster onset of response?
    Neural control, which responds within milliseconds; endocrine responses take seconds to hours or longer.
  11. Which control system, neural or endocrine, mainly regulates long-term processes such as growth, puberty, and metabolic rate?
    The endocrine system, because these processes require sustained signals acting on many tissues.

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