Cell Structure and Organelles - Anatomy and Physiology

  1. Which organelle enlarges in liver cells exposed to drugs such as barbiturates?
    The smooth endoplasmic reticulum, which holds the enzymes that detoxify these drugs.
  2. What are the main functions of peroxisomes?
    Oxidizing very long-chain fatty acids and other molecules, and breaking down hydrogen peroxide with catalase.
  3. What is the main function of the Golgi apparatus?
    Modifying, sorting, and packaging proteins and lipids from the ER into vesicles for their destinations.
  4. What is the internal microtubule arrangement of a motile cilium?
    The 9 + 2 arrangement: nine outer microtubule doublets around a central pair.
  5. What is the function of the centrosome and its centrioles?
    Organizing microtubules, including forming the mitotic spindle during cell division.
  6. What is the function of the nucleolus?
    Making ribosomal RNA and assembling ribosomal subunits.
  7. What is the function of microvilli, and what forms their core?
    They increase surface area for absorption. Their core is a bundle of actin filaments.
  8. Which ribosome-studded organelle is especially abundant in pancreatic acinar cells that secrete digestive enzymes?
    The rough endoplasmic reticulum, which makes large amounts of secretory protein.
  9. What is the main function of mitochondria?
    Producing most of the cell's ATP through aerobic cellular respiration. They contain their own DNA.
  10. What do lysosomes contain, and what is their function?
    Acid hydrolase enzymes in an acidic interior. They digest worn-out organelles, engulfed material, and macromolecules.
  11. What is the main function of the rough endoplasmic reticulum?
    Synthesizing proteins destined for secretion, for membranes, or for lysosomes, on its attached ribosomes.
  12. What are the main functions of the smooth endoplasmic reticulum?
    Lipid and steroid synthesis, detoxification of drugs, and calcium storage (as the sarcoplasmic reticulum in muscle).

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