All GRE Subject Test: Biochemistry, Cell, and Molecular Biology Resources
Example Question #1 : Endoplasmic Reticulum And Golgi Apparatus
Which component of the Golgi apparatus is primarily responsible for "receiving" proteins to be packaged and modified?
The cis Golgi is usually closely apposed to the endoplasmic reticulum, where proteins are synthesized by ribosomes. Once they have left the ribosome, the proteins are already close to the Golgi and are taken up by the cis side of the apparatus. The trans Golgi sends the newly packaged proteins out to their final destinations.
Example Question #2 : Endoplasmic Reticulum And Golgi Apparatus
Which component/suborganelle structure of the Golgi apparatus accepts vesicles from the rough endoplasmic reticulum containing nascent proteins to be processed through the Golgi apparatus?
Medial Golgi stack
Trans Golgi stack
The cis face of the Golgi apparatus is the first part of the apparatus that faces the rough endoplasmic reticulum and interacts with recently synthesized proteins that need to be processed and packaged by the Golgi apparatus. The rest of the structures listed are indeed parts of the Golgi that the proteins must pass through during the course of processing, but the cis face is met first.