GRE Subject Test: Biochemistry, Cell, and Molecular Biology : Help with Golgi Apparatus Function

Study concepts, example questions & explanations for GRE Subject Test: Biochemistry, Cell, and Molecular Biology

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Example Questions

Example Question #1 : Help With Golgi Apparatus Function

What is the primary function of the Golgi apparatus?

Possible Answers:

Maintaining the secretory pathway

All of these are primary functions of the Golgi apparatus

Protein sorting

Post-translational modifications of proteins

Correct answer:

All of these are primary functions of the Golgi apparatus

Explanation:

The Golgi apparatus is a complex organelle with many various functions. These functions are primarily dedicated to protein modification, protein packaging, and protein sorting. Some of post-translational modifications that take place in this organelle include glycosylation and phosphorylation. The Golgi apparatus is an important relay in the secretory pathway, as it produces the vesicles that contain most secreted peptides.

Example Question #2 : Help With Golgi Apparatus Function

Which of the following GTP-binding proteins is associated with COPI during vesicle assembly and budding in the cis-Golgi?

 

Possible Answers:

ATPases

SAR1A

Glycosidases

ADP ribosylation factors (ARFs)

Soluble NSF attachment protein receptor (SNARE)

Correct answer:

ADP ribosylation factors (ARFs)

Explanation:

The correct answer is ADP ribosylation factors (ARFs). ARFs are active when bound by GTP, and inactive when bound by GDP. The active GTP-bound form of ARF binds the vesicle coat protein 1 (COPI), to faciliate vesicle budding from the cis-Golgi face.

Example Question #3 : Help With Golgi Apparatus Function

Each of the following functions are associated with the Golgi apparatus, except __________.

Possible Answers:

Formation of proteoglycans for the extracellular matrix

Delivery of proteins to the lysosome

Post-translational modifications to proteins to aid in their sorting

Contains resident proteins required for the electron transport chain (ETC)

Delivery of proteins to the plasma membrane

Correct answer:

Contains resident proteins required for the electron transport chain (ETC)

Explanation:

The Golgi apparatus is considered the post office of the cell; proteins are received, sorted, modified, and sent to their final cellular destination. The proteins required for the electron transport chain are localized to the mitochondria, and are not within the Golgi apparatus, thus this is the correct selection. 

All GRE Subject Test: Biochemistry, Cell, and Molecular Biology Resources

1 Diagnostic Test 201 Practice Tests Question of the Day Flashcards Learn by Concept
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