GRE Subject Test: Biochemistry, Cell, and Molecular Biology : Help with Enzyme Modification

Study concepts, example questions & explanations for GRE Subject Test: Biochemistry, Cell, and Molecular Biology

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Example Questions

Example Question #1 : Help With Enzyme Modification

Which of the following is an example of allosteric regulation of enzymes?

Possible Answers:

Phosphorylation of an amino acid in the active site

The non-covalent binding of cAMP to the active site

Phosphorylation of an amino acid somewhere other than the active site

The non-covalent binding of cAMP somewhere other than the active site

Correct answer:

The non-covalent binding of cAMP somewhere other than the active site

Explanation:

The difference between the binding of cAMP and phosphorylation is that the latter is a covalent modification. Covalent modifications are a different way to regulate proteins, and do not fall under the category of allosteric regulation. Allosteric regulation only occurs outside of the active site, often simply called an allosteric site. The non-covalent binding of cAMP to a region of an enzyme outside of the active site thus qualifies as allosteric regulation.

All GRE Subject Test: Biochemistry, Cell, and Molecular Biology Resources

1 Diagnostic Test 201 Practice Tests Question of the Day Flashcards Learn by Concept
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